Téléchargez le livre : Genetics of the Mouse
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Description

This book, written by experienced geneticists, covers topics ranging from the natural history of the mouse species, its handling and reproduction in the laboratory, and its classical genetics and cytogenetics, to modern issues including the analysis of the transcriptome, the parental imprinting and X-chromosome inactivation. The strategies for creating all sorts of mutations, either by genetic engineering or by using mutagens, are also reviewed and discussed in detail. Finally, a last chapter outlines the methodology used for the analysis of complex or quantitative traits.
 
The authors also discuss the importance of accurate phenotyping, which is now performed in the mouse clinics established worldwide and identify the limits of the mouse model, which under certain circumstances can fail to present the phenotype expected from the cognate condition in the human model. For each chapter an up-to-date list of pertinent references is provided.
 
In short, this book offers an essential resource for all scientists who use or plan to use mice in their research.
Pages
408 pages
Collection
n.c
Parution
2014-11-29
Marque
Springer
EAN papier
9783662442869
EAN EPUB
9783662442876
Informations sur l'ebook
Nombre pages copiables
4
Nombre pages imprimables
40
Taille du fichier
3881 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
179,34 €

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