Systems Biology of Metabolic and Signaling Networks

Energy, Mass and Information Transfer

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Éditeur :

Springer


Collection :

Springer Series in Biophysics

Paru le : 2013-10-22



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Description

Systems Biology represents a new paradigm aiming at a whole-organism-level understanding of biological phenomena, emphasizing interconnections and functional interrelationships rather than component parts. The study of network properties, and how they control and regulate behavior from the cellular to organism level, constitutes a main focus of Systems Biology. This book addresses from a novel perspective a major unsolved biological problem: understanding how a cell works and what goes wrong in pathology. The task undertaken by the authors is in equal parts conceptual and methodological, integrative and analytical, experimental and theoretical, qualitative and quantitative, didactic and comprehensive. Essentially, they unravel the spatio-temporal unfolding of interacting mass-energy and information networks at the cellular and organ levels, as well as its modulation through activation or repression by signaling networks to produce a certain phenotype or (patho)physiological response.
Starting with the historical roots, in thirteen chapters this work explores the Systems Biology of signaling networks, cellular structures and fluxes, organ and microorganism functions. In doing so, it establishes the basis of a 21st century approach to biological complexity.
Pages
375 pages
Collection
Springer Series in Biophysics
Parution
2013-10-22
Marque
Springer
EAN papier
9783642385049
EAN EPUB
9783642385056

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
37
Taille du fichier
5284 Ko
Prix
147,69 €