Téléchargez le livre : Fc Receptors

Fc Receptors

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Éditeur :

Springer


Collection :

Current Topics in Microbiology and Immunology

Paru le : 2014-08-12

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Description

This volume provides a state-of-the-art update on Fc Receptors (FcRs). It is divided into five parts. Part I, Old and New FcRs, deals with the long-sought-after FcµR and the recently discovered FCRL family and TRIM21. Part II, FcR Signaling, presents a computational model of FceRI signaling, novel calcium channels, and the lipid phosphatase SHIP1. Part III, FcR Biology, addresses major physiological functions of FcRs, their glycosylation, how they induce and regulate both adaptive immune responses and inflammation, especially in vivo, FcR humanized mice, and the multifaceted properties of FcRn. Part IV, FcRs and Disease, discusses FcR polymorphism, FcRs in rheumatoid arthritis and whether their FcRs make macaques good models for studying HIV infection. In Part V, FcRs and Therapeutic Antibodies, the roles of various FcRs, including Fc?RIIB and FcaRI, in the immunotherapy of cancer and autoimmune diseases using monoclonal antibodies and IVIg are highlighted. All 18 chapters were written by respected experts in their fields, offering an invaluable reference source for scientists and clinicians interested in FcRs and how to better master antibodies for therapeutic purposes.
Pages
424 pages
Collection
Current Topics in Microbiology and Immunology
Parution
2014-08-12
Marque
Springer
EAN papier
9783319079103
EAN EPUB
9783319079110
Informations sur l'ebook
Nombre pages copiables
4
Nombre pages imprimables
42
Taille du fichier
3267 Ko
Prix
168,79 €

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