Téléchargez le livre : Proteoglycans in Stem Cells

Proteoglycans in Stem Cells

From Development to Cancer

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Éditeur :

Springer


Collection :

Biology of Extracellular Matrix

Paru le : 2021-06-07



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Description

This book provides a state-of-the-art compendium on the role of proteoglycans and glycosaminoglycans during development and in cancer. It also suggests directions for novel therapeutic and biotechnological applications in stem cell biology.
Proteoglycans and glycosaminoglycans, as part of the extracellular matrix, are multifunctional modulators of growth factor, cytokine, integrin and morphogen signaling, which determine both self-renewal, senescence and/or differentiation of stem cells during development. Since proteoglycans modulate cell adhesion and migration they are important organizers of the extracellular matrix within the proper stem cell niche. A malfunctioning of proteoglycans and glycosaminoglycans contributes to the cancer stem cell phenotype, which is linked to therapeutic resistance and recurrence in malignant disease.
This book is essential reading for anyone interested in the extracellular matrix and its role in development.
The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
Pages
308 pages
Collection
Biology of Extracellular Matrix
Parution
2021-06-07
Marque
Springer
EAN papier
9783030734527
EAN PDF
9783030734534
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
30
Taille du fichier
8950 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
179,34 €
EAN EPUB
9783030734534
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
30
Taille du fichier
50811 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
179,34 €

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