Mitochondria as a Key Intracellular Target of Thallium Toxicity



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Academic Press


Paru le : 2022-06-01



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Description
Mitochondria as a Key Intracellular Target of Thallium Toxicity presents a new hypothesis that explains the decrease in antioxidant defense of thallium poisoning and proposes a new model for studying the transport of inorganic cations across the inner mitochondrial membrane. Readers will learn about the toxicity of thallium and its compounds, the toxicology of thallium, the toxic thallium effects on cells, and the effects of thallium on mitochondria. In addition, the book lists the pathways and mechanisms of thallium transport into cells and mitochondria, including information on toxicity that has been analyzed at both the cellular and subcellular levels. The increase in human contact with the toxic trace element thallium is associated with industry development, the release of metal into the environment from various rocks, and the use of special isotope techniques for studying the vascular bed. - Highlights the differences between the toxic effect of thallium and the action of other heavy metals on cells and mitochondria - Explains why the toxicity of thallium in experiments in vivo is higher than that of bivalent heavy metals - Discusses the applied in vitro model when searching for new inhibitors of the mitochondrial permeability transition pore
Pages
278 pages
Collection
n.c
Parution
2022-06-01
Marque
Academic Press
EAN papier
9780323955317
EAN PDF
9780323955324

Informations sur l'ebook
Nombre pages copiables
27
Nombre pages imprimables
27
Taille du fichier
4813 Ko
Prix
151,92 €
EAN EPUB SANS DRM
9780323955324

Prix
151,92 €

Sergey Korotkov is a Leading Researcher in the Laboratory of Inorganic Ions' Biochemistry at the Sechenov Institute of Evolutionary Physiology and Biochemistry. He graduated from the Chemical Department of St. Petersburg State University in 1979 and defended his PhD thesis at Russian Academy of Sciences in 1987.

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