Autophagy in Stem Cell Maintenance and Differentiation

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Éditeur :

Springer


Paru le : 2022-11-08

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Description


This book covers a wide range of topics that illustrate the various functions of autophagy in stem cells and offers insights on the mechanisms by which autophagy can regulate stem-cell self-renewal and facilitate specific differentiation programs. Stem cells are unique cells present in most multicellular animals and are essential for their survival. They have two unique properties: the ability to self-renew and the ability to differentiate into one or more cell types. These characteristics of stem cells have found immense therapeutic potential in regenerative medicine. Autophagy is a crucial membrane trafficking pathway that is essential for maintaining cellular homeostasis that involves sequestration of non-functional proteins, protein aggregates and damaged organelles in double-membraned vesicles called autophagosomes, which are subsequently targeted to the lysosome for degradation. The primary aim of this book is to provide knowledge of recent developments in our understanding of the role of autophagy in stem cells, including germline stem cells.


Autophagy is considered a promising target for many diseases. Significant efforts are being developed to identify specific modulators of autophagy, which will aid in designing combinatorial therapeutic strategies that will allow significant improvements in regenerative medicine.
Pages
288 pages
Collection
n.c
Parution
2022-11-08
Marque
Springer
EAN papier
9783031173615
EAN PDF
9783031173622

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
28
Taille du fichier
8018 Ko
Prix
179,34 €
EAN EPUB
9783031173622

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
28
Taille du fichier
19364 Ko
Prix
179,34 €

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