Oral Bioavailability

Basic Principles, Advanced Concepts, and Applications de

Éditeur :

Wiley


Collection :

Wiley Series in Drug Discovery and Development

Paru le : 2011-08-04

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Description

Understand and assess the design, delivery, and efficacy of orally administered drugs
A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications is designed to help chemists, biologists, life science researchers, pharmaceutical scientists, pharmacologists, clinicians, and graduate and students become familiar with the fundamentals and practices of the science of oral bioavailability.
The difference in rate and extent between a drug taken orally and the actual amount of a drug reaching the circulatory system, oral bioavailability is an essential parameter for determining the efficacy and adverse effects of new and developing medications, as well as finding an optimal dosing regimen.
This book provides a much-needed one-stop resource to help readers better understand and appreciate the many facets and complex problems of oral bioavailability, including the basic barriers to oral bioavailability, the methods used to determine relevant parameters, and the challenges of drug delivery.
In addition, this comprehensive book discusses biological and physicochemical methods for improving bioavailability, integrates physicochemistry with physiology and molecular biology, and includes several state-of-the-art technologies and approaches?Caco-2 cell culture model, MDCK, and other related cell culture models?which are used to study the science of oral bioavailability.
Pages
560 pages
Collection
Wiley Series in Drug Discovery and Development
Parution
2011-08-04
Marque
Wiley
EAN papier
9780470260999
EAN PDF
9781118067529

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
560
Taille du fichier
8192 Ko
Prix
176,13 €
EAN EPUB
9781118067581

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
560
Taille du fichier
26235 Ko
Prix
176,13 €