Téléchargez le livre : Kinase Inhibitor Drugs

Kinase Inhibitor Drugs

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Éditeur :

Wiley


Collection :

Wiley Series in Drug Discovery and Development

Paru le : 2011-09-20

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Description
A comprehensive resource on case studies of marketed kinase drugs and promising drug trials
Since the discovery of protein kinase activity in 1954, the field of protein kinase drug discovery has advanced dramatically. With the ongoing clinical success of the Bcr-Abl kinase inhibitor Gleevec in the treatment of chronic myelogenous leukemia and seven additional marketed kinase inhibitor drugs, researchers have compelling evidence that kinase inhibitors can be highly efficacious in the treatment of diseases caused by aberrant activity of protein kinase. Currently more than 100 protein kinase inhibitors are in clinical development.
In one comprehensive volume, the editors, Dr. Rongshi Li and Dr. Jeffrey Stafford, present timely and important case studies of marketed kinase drugs and several of the most advanced kinase inhibitors in clinical trials. Kinase Inhibitor Drugs includes:
Case studies from leading investigators and experts in the field that provide firsthand accounts of kinase inhibitor discovery
Current thinking on kinase structure, biochemistry, and signal transduction pathways
Information on state-of-the-art technologies and tools such as structure-based and fragment-based drug discovery
A lineup of clinical-phase growth factor receptor inhibitors
Inhibitors of cell cycle kinases
The discovery of allosteric inhibitors of MEK kinase
Information on pharmacogenomics and its application to kinase inhibitor clinical development
Pages
528 pages
Collection
Wiley Series in Drug Discovery and Development
Parution
2011-09-20
Marque
Wiley
EAN papier
9780470278291
EAN PDF
9780470524954
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
528
Taille du fichier
12564 Ko
Prix
165,58 €
EAN EPUB
9781118210901
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
528
Taille du fichier
22764 Ko
Prix
165,58 €

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