Téléchargez le livre : Evaluation of Drug Candidates for Preclinical Development

Evaluation of Drug Candidates for Preclinical Development

Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology de

, ,

Éditeur :

Wiley


Collection :

Wiley Series in Drug Discovery and Development

Paru le : 2010-01-06

eBook Téléchargement , DRM LCP 🛈 DRM Adobe 🛈
131,82 €
Téléchargement immédiat
Dès validation de votre commande
Image Louise Reader présentation

Louise Reader

Lisez ce titre sur l'application Louise Reader.

badge apple Application Louise Reader
badge Android Application Louise Reader
Description

Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation
It is believed that selecting the "right" drug candidate for development is the key to success. In the last decade, pharmaceutical R&D departments have integrated pharmacokinetics and drug metabolism, pharmaceutics, and toxicology into early drug discovery to improve the assessment of potential drug compounds. Now, Evaluation of Drug Candidates for Preclinical Development provides a complete view and understanding of why absorption-distribution-metabolism-excretion-toxicology (ADMET) plays a pivotal role in drug discovery and development.
Encompassing the three major interrelated areas in which optimization and evaluation of drug developability is most critical?pharmacokinetics and drug metabolism, pharmaceutics, and safety assessment?this unique resource encourages integrated thinking in drug discovery. The contributors to this volume:
Cover drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, stability, drug formulation, preclinical safety assessment, toxicology, and toxicokinetics
Address developability issues that challenge pharma companies, moving beyond isolated experimental results
Reveal connections between the key scientific areas that are critical for successful drug discovery and development
Inspire forward-thinking strategies and decision-making processes in preclinical evaluation to maximize the potential of drug candidates to progress through development efficiently and meet the increasing demands of the marketplace
Evaluation of Drug Candidates for Preclinical Development serves as an introductory reference for those new to the pharmaceutical industry and drug discovery in particular. It is especially well suited for scientists and management teams in small- to mid-sized pharmaceutical companies, as well as academic researchers and graduate students concerned with the practical aspects related to the evaluation of drug developability.
Pages
304 pages
Collection
Wiley Series in Drug Discovery and Development
Parution
2010-01-06
Marque
Wiley
EAN papier
9780470044919
EAN PDF
9780470574881
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
304
Taille du fichier
2150 Ko
Prix
131,82 €

Suggestions personnalisées