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This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by...
Editeur :
Wiley
Parution :
2011-07-08
ePub
Offre spéciale
-18%
61,95€
|
At present, human society is facing a health care crisis that is affecting patients worldwide. In the United States, it is generally believed that the major problem is lack of affordable access to health care (i.e. health insurance). This book takes an unprecedented...
Editeur :
Elsevier Science
Parution :
2011-07-06
epub sans DRM
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This is a second edition to the original published by Springer in 2006. The comprehensive volume takes a textbook approach systematically developing the field by starting from linear models and then moving up to generalized linear and non-linear mixed effects models....
Editeur :
Springer
Parution :
2011-07-01
ePub
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Are you about to sit your pharmacology exams? Do you lack confidence in prescribing? Would it help to have a quick reference, pocket-sized reassurance on common drugs and the conditions that they are used in? The Hands-on Guide to Clinical Pharmacology is the perfect...
Editeur :
Wiley-Blackwell
Parution :
2011-06-20
Collection :
Hands-on Guides
PDF, ePub
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Structural genomics is the systematic determination of 3D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function...
Editeur :
Academic Press
Parution :
2011-05-11
PDF sans DRM
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The majority of cancers present at a relatively advanced stage in which invasion within the primary organ is well established and metastases to lymph and distant organs are either clinically apparent or present at the microscopic level. However, it is increasingly...
Editeur :
Springer
Parution :
2011-05-07
ePub
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The biohealthcare executive in upper-middle management confronts leadership challenges unique to their industry: they manage highly specialized knowledge workers and innovators, compete at the speed of technology, work in a highly regulated environment where "free...
Editeur :
Woodhead Publishing
Parution :
2011-05-05
epub sans DRM
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The trend of outsourcing to India for research and development is catching on fast. Over the last decade, worldwide pharmaceutical and biotechnology companies have made India their choice for a research destination. Initially R&D was inclined more towards developing...
Editeur :
Woodhead Publishing
Parution :
2011-05-05
epub sans DRM
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Folate pathways are essential in metabolism and macromolecule synthesis. Antifolate drugs that are largely transported via a high capacity folate transporter (i.e. the reduced-folate carrier) and inhibit folate-dependent enzymes include the dihydrofolate reductase...
Editeur :
Springer
Parution :
2011-05-05
ePub
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Development of Vaccines: From Discovery to Clinical Testing outlines the critical steps, and analytical tools and techniques, needed to take a vaccine from discovery through a successful clinical trial. Contributions from leading experts in the critical areas of vaccine...
Editeur :
Wiley
Parution :
2011-05-04
PDF, ePub
Offre spéciale
-10%
152,95€
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The Practice of Medicinal Chemistry fills a gap in the list of available medicinal chemistry literature. It is a single-volume source on the practical aspects of medicinal chemistry. Considered ""the Bible"" by medicinal chemists, the book emphasizes the methods that...
Editeur :
Academic Press
Parution :
2011-05-02
PDF sans DRM
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Understanding the role of hedgehog signaling in cancer is critically important for novel cancer therapeutics. The hedgehog pathway is a major pathway regulating cell differentiation, tissue polarity, stem cell maintenance and cell proliferation. It is known by now that...
Editeur :
Springer
Parution :
2011-04-30
ePub
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The ultimate source of information on the design of new anticancer agents, emphasizing small molecules, this newest work covers recent notable successes resulting from the human genome and cancer genomics projects. These advances have provided information on targets...
Editeur :
Academic Press
Parution :
2011-04-28
PDF, epub sans DRM
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Parkinson's disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular...
Editeur :
Academic Press
Parution :
2011-04-28
epub sans DRM
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Novel Anticancer Agents offers pertinent basic science information on strategies used for the rational design and discovery of novel anticancer agents, and, in addition, translational studies involving clinical trial design and execution with these novel, mostly...
Editeur :
Academic Press
Parution :
2011-04-28
PDF, epub sans DRM
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This book guides the reader through FDA regulation guidelines and outlines a comprehensive strategy for cost reduction in regulatory affairs and compliance.This book explains six strategies to cost-effectively comply with FDA regulations while maintaining product safety...
Editeur :
Wiley
Parution :
2011-04-18
PDF, ePub
Offre spéciale
-10%
112,95€
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By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel therapeutics and to target new viruses. It begins with a general discussion...
Editeur :
Wiley-VCH
Parution :
2011-04-08
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional structures of both the small and large molecule are known, their interaction...
Editeur :
Wiley-VCH
Parution :
2011-03-31
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately...
Editeur :
Wiley
Parution :
2011-03-29
ePub
Offre spéciale
-9%
148,95€
|
Molecular Determinants of Radiation Response includes chapters by expert authors who detail the present understanding of key DNA damage response pathways and proteins. The chapters include comprehensive discussions on where and how specific alterations in function of...
Editeur :
Springer
Parution :
2011-03-23
Collection :
Current Cancer Research
ePub
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