Jonathan Schisler has experience in studying metabolism, gene expression signatures, and ubiquitin ligases over the past 14 years. His expertise lies in integration of complex genomic-biologic data to elucidate risk relationships in both murine and human systems with a focus on cardiovascular disease and protein quality control mechanisms. His primary focus is to develop models to integrate datasets derived from clinical genomics, transcriptomics, and metabolomics allowing our lab to further interrogate gene and protein function in health and disease using molecular, cellular and biochemical approaches.